Amin, Kamelia M <br/><br/>
A novel class of substituted spiro [quinazoline-2,1'-cyclohexane] derivatives as effective PPAR-1 inhibitors: molecular modeling, synthesis, cytotoxic and enzyme assay evaluation.  [electronic resource] 

 -  Acta poloniae pharmaceutica   
 - 687-708 p.  digital 
<br/><br/> Publication Type: Comparative Study; Journal Article 
<br/><br/><label>ISSN: </label>0001-6837 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Antineoplastic Agents--chemical synthesis<br/>Benzamides--pharmacology<br/>Binding Sites<br/>Breast Neoplasms--enzymology<br/>Cell Proliferation<br/>Computer-Aided Design<br/>Cyclohexanes--chemical synthesis<br/>Doxorubicin--pharmacology<br/>Drug Design<br/>Enzyme Inhibitors--chemical synthesis<br/>Female<br/>Humans<br/>MCF-7 Cells<br/>Molecular Docking Simulation<br/>Poly (ADP-Ribose) Polymerase-1<br/>Poly(ADP-ribose) Polymerase Inhibitors<br/>Poly(ADP-ribose) Polymerases--chemistry<br/>Protein Conformation<br/>Quinazolines--chemical synthesis