TY - GEN AU - Yu,Xing Xian AU - Watts,Lynnetta M AU - Manchem,Vara Prasad AU - Chakravarty,Kaushik AU - Monia,Brett P AU - McCaleb,Michael L AU - Bhanot,Sanjay TI - Peripheral reduction of FGFR4 with antisense oligonucleotides increases metabolic rate and lowers adiposity in diet-induced obese mice SN - 1932-6203 PY - 2014///0218 KW - Adiposity KW - drug effects KW - Animals KW - Basal Metabolism KW - Bile Acids and Salts KW - metabolism KW - Body Weight KW - Caloric Restriction KW - Diet KW - Drug Therapy, Combination KW - Fatty Acids KW - Fatty Liver KW - blood KW - Feeding Behavior KW - Fibroblast Growth Factors KW - Gene Expression Regulation KW - Hepatocytes KW - Insulin KW - pharmacology KW - Liver KW - Mice KW - Mice, Inbred C57BL KW - Mice, Obese KW - Obesity KW - Oligonucleotides, Antisense KW - Oxidation-Reduction KW - Piperidines KW - Pyrazoles KW - Receptor, Cannabinoid, CB1 KW - antagonists & inhibitors KW - Receptor, Fibroblast Growth Factor, Type 4 KW - genetics KW - Rimonabant N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1371/journal.pone.0066923 ER -