Tai, Wei-Tien

Discovery of novel Src homology region 2 domain-containing phosphatase 1 agonists from sorafenib for the treatment of hepatocellular carcinoma. [electronic resource] - Hepatology (Baltimore, Md.) Jan 2014 - 190-201 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1527-3350

10.1002/hep.26640 doi


Animals
Antineoplastic Agents--pharmacology
Apoptosis--drug effects
Carcinoma, Hepatocellular--drug therapy
Catalytic Domain
Cell Line, Tumor
Drug Resistance, Neoplasm--drug effects
Humans
Liver Neoplasms--drug therapy
Mice
Models, Molecular
Niacinamide--analogs & derivatives
Phenylurea Compounds--pharmacology
Protein Tyrosine Phosphatase, Non-Receptor Type 6--chemistry
Random Allocation
STAT3 Transcription Factor--antagonists & inhibitors
Sorafenib
Xenograft Model Antitumor Assays