Discovery of novel Src homology region 2 domain-containing phosphatase 1 agonists from sorafenib for the treatment of hepatocellular carcinoma. [electronic resource]
- Hepatology (Baltimore, Md.) Jan 2014
- 190-201 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1527-3350
10.1002/hep.26640 doi
Animals Antineoplastic Agents--pharmacology Apoptosis--drug effects Carcinoma, Hepatocellular--drug therapy Catalytic Domain Cell Line, Tumor Drug Resistance, Neoplasm--drug effects Humans Liver Neoplasms--drug therapy Mice Models, Molecular Niacinamide--analogs & derivatives Phenylurea Compounds--pharmacology Protein Tyrosine Phosphatase, Non-Receptor Type 6--chemistry Random Allocation STAT3 Transcription Factor--antagonists & inhibitors Sorafenib Xenograft Model Antitumor Assays