TY  - GEN
AU  - Farinha,Carlos M
AU  - King-Underwood,John
AU  - Sousa,Marisa
AU  - Correia,Ana Raquel
AU  - Henriques,Bárbara J
AU  - Roxo-Rosa,Mónica
AU  - Da Paula,Ana Carina
AU  - Williams,Jonathan
AU  - Hirst,Simon
AU  - Gomes,Cláudio M
AU  - Amaral,Margarida D
TI  - Revertants, low temperature, and correctors reveal the mechanism of F508del-CFTR rescue by VX-809 and suggest multiple agents for full correction
SN  - 1879-1301
PY  - 2014///0623
KW  - Aminopyridines
KW  - pharmacology
KW  - Benzodioxoles
KW  - Cystic Fibrosis Transmembrane Conductance Regulator
KW  - chemistry
KW  - Drug Synergism
KW  - Endoplasmic Reticulum
KW  - drug effects
KW  - Humans
KW  - Kinetics
KW  - Models, Molecular
KW  - Nucleotides
KW  - metabolism
KW  - Protein Folding
KW  - Protein Structure, Tertiary
KW  - Sequence Deletion
KW  - Temperature
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.chembiol.2013.06.004
ER  -