Farinha, Carlos M <br/><br/>
Revertants, low temperature, and correctors reveal the mechanism of F508del-CFTR rescue by VX-809 and suggest multiple agents for full correction.  [electronic resource] 

 -  Chemistry & biology  Jul 2013 
 - 943-55 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1879-1301 
<br/><br/><label>Standard No.: </label>10.1016/j.chembiol.2013.06.004  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Aminopyridines--pharmacology<br/>Benzodioxoles--pharmacology<br/>Cystic Fibrosis Transmembrane Conductance Regulator--chemistry<br/>Drug Synergism<br/>Endoplasmic Reticulum--drug effects<br/>Humans<br/>Kinetics<br/>Models, Molecular<br/>Nucleotides--metabolism<br/>Protein Folding--drug effects<br/>Protein Structure, Tertiary<br/>Sequence Deletion--drug effects<br/>Temperature