TY  - GEN
AU  - Mereniuk,Todd R
AU  - El Gendy,Mohamed A M
AU  - Mendes-Pereira,Ana M
AU  - Lord,Christopher J
AU  - Ghosh,Sunita
AU  - Foley,Edan
AU  - Ashworth,Alan
AU  - Weinfeld,Michael
TI  - Synthetic lethal targeting of PTEN-deficient cancer cells using selective disruption of polynucleotide kinase/phosphatase
SN  - 1538-8514
PY  - 2014///0519
KW  - Apoptosis
KW  - genetics
KW  - Cell Line, Tumor
KW  - DNA Breaks, Double-Stranded
KW  - DNA Repair
KW  - DNA Repair Enzymes
KW  - antagonists & inhibitors
KW  - Gene Knockout Techniques
KW  - HCT116 Cells
KW  - Humans
KW  - Molecular Targeted Therapy
KW  - Neoplasms
KW  - drug therapy
KW  - PTEN Phosphohydrolase
KW  - Phosphotransferases (Alcohol Group Acceptor)
KW  - RNA, Small Interfering
KW  - Radiation Tolerance
KW  - drug effects
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1158/1535-7163.MCT-12-1093
ER  -