TY  - GEN
AU  - Fregoso,Oliver I
AU  - Ahn,Jinwoo
AU  - Wang,Chuanping
AU  - Mehrens,Jennifer
AU  - Skowronski,Jacek
AU  - Emerman,Michael
TI  - Evolutionary toggling of Vpx/Vpr specificity results in divergent recognition of the restriction factor SAMHD1
SN  - 1553-7374
PY  - 2014///0218
KW  - Animals
KW  - Cercopithecinae
KW  - Databases, Protein
KW  - Evolution, Molecular
KW  - HEK293 Cells
KW  - HIV-2
KW  - genetics
KW  - Host-Pathogen Interactions
KW  - Humans
KW  - Models, Biological
KW  - Monomeric GTP-Binding Proteins
KW  - chemistry
KW  - Mutant Proteins
KW  - Peptide Fragments
KW  - Phylogeny
KW  - Proteasome Endopeptidase Complex
KW  - Protein Interaction Domains and Motifs
KW  - Protein Stability
KW  - Recombinant Fusion Proteins
KW  - SAM Domain and HD Domain-Containing Protein 1
KW  - Simian Immunodeficiency Virus
KW  - Ubiquitination
KW  - Viral Regulatory and Accessory Proteins
KW  - vpr Gene Products, Human Immunodeficiency Virus
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural
UR  - https://doi.org/10.1371/journal.ppat.1003496
ER  -