TY  - GEN
AU  - Maslov,Mikhail Y
AU  - Edelman,Elazer R
AU  - Wei,Abraham E
AU  - Pezone,Matthew J
AU  - Lovich,Mark A
TI  - High concentrations of drug in target tissues following local controlled release are utilized for both drug distribution and biologic effect: an example with epicardial inotropic drug delivery
SN  - 1873-4995
PY  - 2014///0414
KW  - Alginates
KW  - chemistry
KW  - Animals
KW  - Calcium
KW  - Cardiotonic Agents
KW  - administration & dosage
KW  - Cyclic AMP
KW  - metabolism
KW  - Delayed-Action Preparations
KW  - Drug Delivery Systems
KW  - Epinephrine
KW  - Glucuronic Acid
KW  - Heart Ventricles
KW  - Hexuronic Acids
KW  - Hydrogels
KW  - Infusions, Intravenous
KW  - Male
KW  - Myocardial Contraction
KW  - drug effects
KW  - Pericardium
KW  - Rats
KW  - Rats, Sprague-Dawley
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.jconrel.2013.06.038
ER  -