Markova, S M

Association of CYP2C9*2 with bosentan-induced liver injury. [electronic resource] - Clinical pharmacology and therapeutics Dec 2013 - 678-86 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1532-6535

10.1038/clpt.2013.143 doi


Alanine Transaminase--metabolism
Aryl Hydrocarbon Hydroxylases--genetics
Aspartate Aminotransferases--metabolism
Bosentan
Chemical and Drug Induced Liver Injury--enzymology
Cytochrome P-450 CYP2C9
Endothelin Receptor Antagonists
Female
Genetic Association Studies
Genetic Markers
HEK293 Cells
Humans
Hypertension, Pulmonary--drug therapy
Liver-Specific Organic Anion Transporter 1
Male
Middle Aged
Multidrug Resistance-Associated Protein 2
Organic Anion Transporters--genetics
Polymorphism, Single Nucleotide
Sulfonamides--adverse effects