TY - GEN AU - Zhong,Hui-ming AU - Ding,Qian-hai AU - Chen,Wei-ping AU - Luo,Ru-bin TI - Vorinostat, a HDAC inhibitor, showed anti-osteoarthritic activities through inhibition of iNOS and MMP expression, p38 and ERK phosphorylation and blocking NF-κB nuclear translocation SN - 1878-1705 PY - 2014///0422 KW - Active Transport, Cell Nucleus KW - drug effects KW - Aged KW - Cell Nucleus KW - metabolism KW - Cells, Cultured KW - Chondrocytes KW - Extracellular Signal-Regulated MAP Kinases KW - Histone Deacetylase Inhibitors KW - pharmacology KW - Humans KW - Hydroxamic Acids KW - Interleukin-1beta KW - immunology KW - Matrix Metalloproteinase 1 KW - Matrix Metalloproteinase 13 KW - Middle Aged KW - NF-kappa B KW - Nitric Oxide Synthase Type II KW - Osteoarthritis KW - drug therapy KW - Phosphorylation KW - Signal Transduction KW - Tissue Inhibitor of Metalloproteinase-1 KW - Vorinostat KW - p38 Mitogen-Activated Protein Kinases N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.intimp.2013.06.027 ER -