TY - GEN AU - Islam,Anowara AU - Li,Shu Shun AU - Oykhman,Paul AU - Timm-McCann,Martina AU - Huston,Shaunna M AU - Stack,Danuta AU - Xiang,Richard F AU - Kelly,Margaret M AU - Mody,Christopher H TI - An acidic microenvironment increases NK cell killing of Cryptococcus neoformans and Cryptococcus gattii by enhancing perforin degranulation SN - 1553-7374 PY - 2014///0218 KW - Cell Adhesion KW - Cell Degranulation KW - Cell Line KW - Cells, Cultured KW - Cellular Microenvironment KW - Cerebral Cortex KW - immunology KW - Cryptococcosis KW - Cryptococcus gattii KW - Cryptococcus neoformans KW - Cytotoxicity, Immunologic KW - Fungal Proteins KW - genetics KW - Humans KW - Hydrogen-Ion Concentration KW - Killer Cells, Natural KW - Lung KW - MAP Kinase Signaling System KW - Perforin KW - metabolism KW - Phosphorylation KW - Protein Processing, Post-Translational KW - Up-Regulation KW - Virus Replication KW - ras Proteins N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1371/journal.ppat.1003439 ER -