TY - GEN AU - Schepers,Koen AU - Pietras,Eric M AU - Reynaud,Damien AU - Flach,Johanna AU - Binnewies,Mikhail AU - Garg,Trit AU - Wagers,Amy J AU - Hsiao,Edward C AU - Passegué,Emmanuelle TI - Myeloproliferative neoplasia remodels the endosteal bone marrow niche into a self-reinforcing leukemic niche SN - 1875-9777 PY - 2014///0408 KW - Animals KW - Bone Marrow KW - physiology KW - Cell Transdifferentiation KW - Cells, Cultured KW - Chemokine CCL3 KW - metabolism KW - Hematopoietic Stem Cell Transplantation KW - Humans KW - Leukemia KW - complications KW - Mesenchymal Stem Cells KW - Mice KW - Mice, Transgenic KW - Myeloproliferative Disorders KW - Neoplastic Stem Cells KW - Primary Myelofibrosis KW - etiology KW - Receptors, Notch KW - Stem Cell Niche KW - Thrombopoietin KW - Transforming Growth Factor beta N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.stem.2013.06.009 ER -