Schepers, Koen

Myeloproliferative neoplasia remodels the endosteal bone marrow niche into a self-reinforcing leukemic niche. [electronic resource] - Cell stem cell Sep 2013 - 285-99 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1875-9777

10.1016/j.stem.2013.06.009 doi


Animals
Bone Marrow--physiology
Cell Transdifferentiation
Cells, Cultured
Chemokine CCL3--metabolism
Hematopoietic Stem Cell Transplantation
Humans
Leukemia--complications
Mesenchymal Stem Cells--physiology
Mice
Mice, Transgenic
Myeloproliferative Disorders--complications
Neoplastic Stem Cells--physiology
Primary Myelofibrosis--etiology
Receptors, Notch--metabolism
Stem Cell Niche
Thrombopoietin--metabolism
Transforming Growth Factor beta--metabolism