Lee, Chunja

Downregulation of mouse hepatic CYP3A protein by 3-methylcholanthrene does not require cytochrome P450-dependent metabolism. [electronic resource] - Drug metabolism and disposition: the biological fate of chemicals Oct 2013 - 1782-6 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1521-009X

10.1124/dmd.113.052993 doi


Animals
Cytochrome P-450 CYP3A
Cytochrome P-450 Enzyme System--genetics
Down-Regulation--drug effects
Hepatocytes--drug effects
Liver--drug effects
Male
Methylcholanthrene--pharmacology
Mice
Mice, Inbred C57BL
Microsomes, Liver--enzymology
NADPH-Ferrihemoprotein Reductase--genetics
Oxygenases--genetics
RNA, Messenger--genetics
Receptors, Aryl Hydrocarbon--genetics