Sceneay, Jaclyn <br/><br/>
The antioxidant N-acetylcysteine prevents HIF-1 stabilization under hypoxia in vitro but does not affect tumorigenesis in multiple breast cancer models in vivo.  [electronic resource] 

 -  PloS one  2013 
 - e66388 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1932-6203 
<br/><br/><label>Standard No.: </label>10.1371/journal.pone.0066388  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Acetylcysteine--pharmacology<br/>Animals<br/>Antineoplastic Agents--pharmacology<br/>Antioxidants--pharmacology<br/>Apoptosis--drug effects<br/>Carcinogenesis<br/>Cell Hypoxia<br/>Cell Line, Tumor<br/>Cell Proliferation--drug effects<br/>Drug Screening Assays, Antitumor<br/>Epithelial-Mesenchymal Transition<br/>Female<br/>Glutathione--blood<br/>Hypoxia-Inducible Factor 1, alpha Subunit--metabolism<br/>Lung Neoplasms--blood supply<br/>Mammary Neoplasms, Experimental--blood supply<br/>Mice<br/>Mice, Inbred BALB C<br/>Mice, Inbred C57BL<br/>Neoplasm Transplantation<br/>Neovascularization, Pathologic--metabolism<br/>Phenotype<br/>Protein Stability<br/>Tumor Burden--drug effects<br/>Vascular Endothelial Growth Factor A--metabolism