TY - GEN AU - Zhang,Yi AU - Zhao,Li AU - Li,Xin AU - Wang,Yajing AU - Yao,Jing AU - Wang,Hu AU - Li,Fanni AU - Li,Zhiyu AU - Guo,Qinglong TI - V8, a newly synthetic flavonoid, induces apoptosis through ROS-mediated ER stress pathway in hepatocellular carcinoma SN - 1432-0738 PY - 2014///1028 KW - Animals KW - Antineoplastic Agents KW - chemical synthesis KW - Apoptosis KW - drug effects KW - Carcinoma, Hepatocellular KW - drug therapy KW - Cell Proliferation KW - Dose-Response Relationship, Drug KW - Endoplasmic Reticulum Chaperone BiP KW - Endoplasmic Reticulum Stress KW - Female KW - Flavanones KW - chemistry KW - Flavones KW - Hep G2 Cells KW - Humans KW - Inhibitory Concentration 50 KW - Liver Neoplasms KW - Membrane Potential, Mitochondrial KW - Mice KW - Reactive Oxygen Species KW - metabolism KW - Signal Transduction KW - Transcription Factor CHOP KW - genetics KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1007/s00204-013-1085-6 ER -