Durmus, S <br/><br/>
P-glycoprotein (MDR1/ABCB1) and breast cancer resistance protein (BCRP/ABCG2) restrict brain accumulation of the JAK1/2 inhibitor, CYT387.  [electronic resource] 

 -  Pharmacological research  Oct 2013 
 - 9-16 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1096-1186 
<br/><br/><label>Standard No.: </label>10.1016/j.phrs.2013.06.009  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>ATP Binding Cassette Transporter, Subfamily B--genetics<br/>ATP Binding Cassette Transporter, Subfamily B, Member 1--metabolism<br/>ATP Binding Cassette Transporter, Subfamily G, Member 2<br/>ATP-Binding Cassette Transporters--genetics<br/>Animals<br/>Benzamides--blood<br/>Brain--metabolism<br/>Cell Line<br/>Female<br/>Gene Deletion<br/>Humans<br/>Janus Kinase 1--antagonists & inhibitors<br/>Janus Kinase 2--antagonists & inhibitors<br/>Janus Kinases--antagonists & inhibitors<br/>Mice<br/>Neoplasm Proteins--metabolism<br/>Pyrimidines--blood<br/>ATP-Binding Cassette Sub-Family B Member 4