TY - GEN AU - Xing,Junji AU - Ni,Liwen AU - Wang,Shuai AU - Wang,Kezhen AU - Lin,Rongtuan AU - Zheng,Chunfu TI - Herpes simplex virus 1-encoded tegument protein VP16 abrogates the production of beta interferon (IFN) by inhibiting NF-κB activation and blocking IFN regulatory factor 3 to recruit its coactivator CBP SN - 1098-5514 PY - 2013///1125 KW - Animals KW - CREB-Binding Protein KW - metabolism KW - Chlorocebus aethiops KW - HEK293 Cells KW - HeLa Cells KW - Herpes Simplex Virus Protein Vmw65 KW - chemistry KW - Herpesvirus 1, Human KW - genetics KW - Host-Pathogen Interactions KW - Humans KW - Immunity, Innate KW - Interferon Regulatory Factor-3 KW - antagonists & inhibitors KW - Interferon Regulatory Factor-7 KW - Interferon-beta KW - biosynthesis KW - Promoter Regions, Genetic KW - Protein Structure, Tertiary KW - Sendai virus KW - immunology KW - Transcription Factor RelA KW - Transcriptional Activation KW - Vero Cells N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1128/JVI.01440-13 ER -