Di Bartolomeo, M
Lack of KRAS, NRAS, BRAF and TP53 mutations improves outcome of elderly metastatic colorectal cancer patients treated with cetuximab, oxaliplatin and UFT. [electronic resource]
- Targeted oncology Jun 2014
- 155-62 p. digital
Publication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study
ISSN: 1776-260X
Standard No.: 10.1007/s11523-013-0283-8 doi
Subjects--Topical Terms: Adenocarcinoma--drug therapy Aged Aged, 80 and over Antibodies, Monoclonal, Humanized--administration & dosage Antineoplastic Combined Chemotherapy Protocols--administration & dosage Biomarkers, Tumor--genetics Cetuximab Colorectal Neoplasms--drug therapy DNA Mutational Analysis Disease-Free Survival Drug Resistance, Neoplasm--genetics Female GTP Phosphohydrolases--genetics Humans Kaplan-Meier Estimate Male Membrane Proteins--genetics Mutation Nuclear Proteins--genetics Organoplatinum Compounds--administration & dosage Oxaliplatin Proto-Oncogene Proteins--genetics Proto-Oncogene Proteins B-raf--genetics Proto-Oncogene Proteins p21(ras) Reverse Transcriptase Polymerase Chain Reaction Tegafur--administration & dosage Transcription Factors--genetics Tumor Suppressor Protein p53--genetics Uracil--administration & dosage ras Proteins--genetics