Liu, Joyce F
A Phase 1 trial of the poly(ADP-ribose) polymerase inhibitor olaparib (AZD2281) in combination with the anti-angiogenic cediranib (AZD2171) in recurrent epithelial ovarian or triple-negative breast cancer. [electronic resource]
- European journal of cancer (Oxford, England : 1990) Sep 2013
- 2972-8 p. digital
Publication Type: Clinical Trial, Phase I; Journal Article; Research Support, N.I.H., Extramural
ISSN: 1879-0852
Standard No.: 10.1016/j.ejca.2013.05.020 doi
Subjects--Topical Terms: Administration, Oral Adult Aged Antineoplastic Combined Chemotherapy Protocols--adverse effects Breast Neoplasms--drug therapy Capsules Carcinoma, Ovarian Epithelial Diarrhea--chemically induced Dose-Response Relationship, Drug Drug Administration Schedule Fatigue--chemically induced Female Humans Middle Aged Nausea--chemically induced Neoplasm Recurrence, Local Neoplasms, Glandular and Epithelial--drug therapy Ovarian Neoplasms--drug therapy Phthalazines--administration & dosage Piperazines--administration & dosage Poly(ADP-ribose) Polymerase Inhibitors Quinazolines--administration & dosage Receptor, ErbB-2--metabolism Receptors, Estrogen--metabolism Receptors, Progesterone--metabolism Receptors, Vascular Endothelial Growth Factor--antagonists & inhibitors Tablets Treatment Outcome