Clearance of the mutant androgen receptor in motoneuronal models of spinal and bulbar muscular atrophy. [electronic resource]
- Neurobiology of aging Nov 2013
- 2585-603 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1558-1497
10.1016/j.neurobiolaging.2013.05.026 doi
Adaptor Proteins, Signal Transducing--metabolism Adenine--analogs & derivatives Animals Autophagy--drug effects Cell Line, Transformed Cysteine Proteinase Inhibitors--pharmacology Dose-Response Relationship, Drug Gene Expression Regulation--drug effects Green Fluorescent Proteins--genetics HSP20 Heat-Shock Proteins--genetics Heat-Shock Proteins--metabolism Humans Leupeptins--pharmacology Mice Molecular Chaperones Motor Neurons--drug effects Muscle Proteins--genetics Mutation--genetics RNA, Small Interfering--pharmacology Receptors, Androgen--genetics Sequestosome-1 Protein Signal Transduction--drug effects Testosterone--pharmacology Trehalose--pharmacology