TY - GEN AU - Aleksenko,Svetlana S AU - Matczuk,Magdalena AU - Lu,Xifeng AU - Foteeva,Lidia S AU - Pawlak,Katarzyna AU - Timerbaev,Andrei R AU - Jarosz,Maciej TI - Metallomics for drug development: an integrated CE-ICP-MS and ICP-MS approach reveals the speciation changes for an investigational ruthenium(III) drug bound to holo-transferrin in simulated cancer cytosol SN - 1756-591X PY - 2014///0227 KW - Antineoplastic Agents KW - chemistry KW - Ascorbic Acid KW - Blood Proteins KW - Cell Proliferation KW - drug effects KW - Cytosol KW - Drug Design KW - Electrophoresis, Capillary KW - methods KW - Glutathione KW - Humans KW - Ligands KW - Mass Spectrometry KW - Neoplasms KW - pathology KW - Oxidation-Reduction KW - Protein Binding KW - Ruthenium KW - Time Factors KW - Transferrin N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1039/c3mt00092c ER -