TY  - GEN
AU  - Richter,Susan
AU  - Morrison,Shona
AU  - Connor,Tim
AU  - Su,Jiechuang
AU  - Print,Cristin G
AU  - Ronimus,Ron S
AU  - McGee,Sean L
AU  - Wilson,William R
TI  - Zinc finger nuclease mediated knockout of ADP-dependent glucokinase in cancer cell lines: effects on cell survival and mitochondrial oxidative metabolism
SN  - 1932-6203
PY  - 2014///0130
KW  - Animals
KW  - Base Sequence
KW  - Cell Hypoxia
KW  - Cell Proliferation
KW  - Cell Survival
KW  - Deoxyribonucleases, Type II Site-Specific
KW  - chemistry
KW  - Female
KW  - Frameshift Mutation
KW  - Gene Dosage
KW  - Gene Knockout Techniques
KW  - Genetic Engineering
KW  - methods
KW  - Glucokinase
KW  - genetics
KW  - Glycolysis
KW  - HCT116 Cells
KW  - Hexokinase
KW  - Humans
KW  - Mice
KW  - Mice, Nude
KW  - Mitochondria
KW  - metabolism
KW  - Molecular Sequence Data
KW  - Neoplasm Transplantation
KW  - Oxidative Phosphorylation
KW  - Oxygen Consumption
KW  - Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha
KW  - Transcription Factors
KW  - Transcriptome
KW  - Tumor Burden
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1371/journal.pone.0065267
ER  -