Callegari, Ernesto <br/><br/>
Drug metabolites as cytochrome p450 inhibitors: a retrospective analysis and proposed algorithm for evaluation of the pharmacokinetic interaction potential of metabolites in drug discovery and development.  [electronic resource] 

 -  Drug metabolism and disposition: the biological fate of chemicals  Dec 2013 
 - 2047-55 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1521-009X 
<br/><br/><label>Standard No.: </label>10.1124/dmd.113.052241  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Algorithms<br/>Area Under Curve<br/>Biotransformation--physiology<br/>Cytochrome P-450 Enzyme Inhibitors<br/>Cytochrome P-450 Enzyme System--metabolism<br/>Databases, Factual<br/>Drug Discovery--methods<br/>Drug Interactions--physiology<br/>Humans<br/>Pharmaceutical Preparations--metabolism<br/>Retrospective Studies