TY  - GEN
AU  - Huai,Jisen
AU  - Vögtle,F-Nora
AU  - Jöckel,Lars
AU  - Li,Yunbo
AU  - Kiefer,Thomas
AU  - Ricci,Jean-Ehrland
AU  - Borner,Christoph
TI  - TNFα-induced lysosomal membrane permeability is downstream of MOMP and triggered by caspase-mediated NDUFS1 cleavage and ROS formation
SN  - 1477-9137
PY  - 2014///0425
KW  - Animals
KW  - Apoptosis
KW  - Apoptotic Protease-Activating Factor 1
KW  - deficiency
KW  - Caspase 3
KW  - Caspase 7
KW  - Caspase 9
KW  - Cathepsin B
KW  - Cathepsin L
KW  - Cell Membrane
KW  - metabolism
KW  - Cell Membrane Permeability
KW  - physiology
KW  - Cycloheximide
KW  - pharmacology
KW  - Electron Transport Complex I
KW  - Enzyme Activation
KW  - HeLa Cells
KW  - Humans
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - Mice, Knockout
KW  - Mitochondria
KW  - Mitochondrial Membranes
KW  - NADH Dehydrogenase
KW  - biosynthesis
KW  - Organophosphorus Compounds
KW  - Protein Synthesis Inhibitors
KW  - Reactive Oxygen Species
KW  - Tumor Necrosis Factor-alpha
KW  - Ubiquinone
KW  - analogs & derivatives
KW  - bcl-2 Homologous Antagonist-Killer Protein
KW  - bcl-2-Associated X Protein
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1242/jcs.129999
ER  -