Huai, Jisen

TNFα-induced lysosomal membrane permeability is downstream of MOMP and triggered by caspase-mediated NDUFS1 cleavage and ROS formation. [electronic resource] - Journal of cell science Sep 2013 - 4015-25 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1477-9137

10.1242/jcs.129999 doi


Animals
Apoptosis
Apoptotic Protease-Activating Factor 1--deficiency
Caspase 3--deficiency
Caspase 7--deficiency
Caspase 9--deficiency
Cathepsin B--deficiency
Cathepsin L--deficiency
Cell Membrane--metabolism
Cell Membrane Permeability--physiology
Cycloheximide--pharmacology
Electron Transport Complex I--metabolism
Enzyme Activation
HeLa Cells
Humans
Mice
Mice, Inbred C57BL
Mice, Knockout
Mitochondria--metabolism
Mitochondrial Membranes--metabolism
NADH Dehydrogenase--biosynthesis
Organophosphorus Compounds--pharmacology
Protein Synthesis Inhibitors--pharmacology
Reactive Oxygen Species
Tumor Necrosis Factor-alpha--metabolism
Ubiquinone--analogs & derivatives
bcl-2 Homologous Antagonist-Killer Protein--deficiency
bcl-2-Associated X Protein--deficiency