TY - GEN AU - Castro,Josué Joram AU - Méndez,Juan Pablo AU - Coral-Vázquez,Ramón Mauricio AU - Soriano-Ursúa,Marvin Antonio AU - Damian-Matsumura,Pablo AU - Benítez-Granados,Jesús AU - Rosas-Vargas,Haydee AU - Canto,Patricia TI - In vitro and molecular modeling analysis of two mutant desert hedgehog proteins associated with 46,XY gonadal dysgenesis SN - 1557-7430 PY - 2013///1024 KW - Amino Acid Substitution KW - Computational Biology KW - Genetic Predisposition to Disease KW - Gonadal Dysgenesis, 46,XY KW - genetics KW - Gonadal Dysgenesis, Mixed KW - HEK293 Cells KW - Hedgehog Proteins KW - Humans KW - Molecular Dynamics Simulation KW - Mutagenesis, Site-Directed KW - Point Mutation KW - Protein Stability KW - Protein Structure, Secondary N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1089/dna.2013.2052 ER -