TY - GEN AU - Li,Yanhua AU - Zhu,Longchao AU - Lawson,Steven R AU - Fang,Ying TI - Targeted mutations in a highly conserved motif of the nsp1β protein impair the interferon antagonizing activity of porcine reproductive and respiratory syndrome virus SN - 1465-2099 PY - 2013///1106 KW - Amino Acid Sequence KW - Amino Acid Substitution KW - Animals KW - Cell Line KW - Cysteine Proteases KW - genetics KW - DNA Mutational Analysis KW - Host-Pathogen Interactions KW - Humans KW - Immune Evasion KW - Interferons KW - antagonists & inhibitors KW - Macrophages KW - virology KW - Molecular Sequence Data KW - Mutagenesis, Site-Directed KW - Mutant Proteins KW - Porcine respiratory and reproductive syndrome virus KW - Reverse Genetics KW - Viral Nonstructural Proteins N1 - Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S UR - https://doi.org/10.1099/vir.0.051748-0 ER -