Chronic low dose tumor necrosis factor-α (TNF) suppresses early bone accrual in young mice by inhibiting osteoblasts without affecting osteoclasts. [electronic resource]
- Bone Sep 2013
- 174-83 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
1873-2763
10.1016/j.bone.2013.06.002 doi
Aging--drug effects Animals Biomarkers--metabolism Bone and Bones--cytology Cell Differentiation--drug effects Cell Line Cells, Cultured Female Male Mesenchymal Stem Cells--cytology Mice Mice, Inbred C57BL Mice, Transgenic Osteoblasts--cytology Osteoclasts--cytology Tumor Necrosis Factor-alpha--administration & dosage Wnt Signaling Pathway--drug effects