TY - GEN AU - Klinger,Bertram AU - Sieber,Anja AU - Fritsche-Guenther,Raphaela AU - Witzel,Franziska AU - Berry,Leanne AU - Schumacher,Dirk AU - Yan,Yibing AU - Durek,Pawel AU - Merchant,Mark AU - Schäfer,Reinhold AU - Sers,Christine AU - Blüthgen,Nils TI - Network quantification of EGFR signaling unveils potential for targeted combination therapy SN - 1744-4292 PY - 2013///0913 KW - Animals KW - Antineoplastic Agents KW - pharmacology KW - Cell Line, Tumor KW - Colorectal Neoplasms KW - drug therapy KW - Drug Screening Assays, Antitumor KW - Drug Therapy, Combination KW - ErbB Receptors KW - genetics KW - Extracellular Signal-Regulated MAP Kinases KW - Gene Expression Regulation, Neoplastic KW - drug effects KW - Humans KW - Mice KW - Mice, Nude KW - Models, Genetic KW - Phosphatidylinositol 3-Kinases KW - Protein Interaction Maps KW - Protein Kinase Inhibitors KW - Proto-Oncogene Proteins B-raf KW - Proto-Oncogene Proteins c-akt KW - Signal Transduction KW - Transplantation, Heterologous KW - Tumor Burden KW - ras Proteins N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/msb.2013.29 ER -