Klinger, Bertram
Network quantification of EGFR signaling unveils potential for targeted combination therapy. [electronic resource]
- Molecular systems biology 2013
- 673 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
ISSN: 1744-4292
Standard No.: 10.1038/msb.2013.29 doi
Subjects--Topical Terms: Animals Antineoplastic Agents--pharmacology Cell Line, Tumor Colorectal Neoplasms--drug therapy Drug Screening Assays, Antitumor Drug Therapy, Combination ErbB Receptors--genetics Extracellular Signal-Regulated MAP Kinases--genetics Gene Expression Regulation, Neoplastic--drug effects Humans Mice Mice, Nude Models, Genetic Phosphatidylinositol 3-Kinases--genetics Protein Interaction Maps--drug effects Protein Kinase Inhibitors--pharmacology Proto-Oncogene Proteins B-raf--genetics Proto-Oncogene Proteins c-akt--genetics Signal Transduction--drug effects Transplantation, Heterologous Tumor Burden--drug effects ras Proteins--genetics