TY - GEN AU - Lovell,Kimberly M AU - Felts,Andrew S AU - Rodriguez,Alice L AU - Venable,Daryl F AU - Cho,Hyekyung P AU - Morrison,Ryan D AU - Byers,Frank W AU - Daniels,J Scott AU - Niswender,Colleen M AU - Conn,P Jeffrey AU - Lindsley,Craig W AU - Emmitte,Kyle A TI - N-Acyl-N'-arylpiperazines as negative allosteric modulators of mGlu1: identification of VU0469650, a potent and selective tool compound with CNS exposure in rats SN - 1464-3405 PY - 2014///0113 KW - Allosteric Regulation KW - drug effects KW - Animals KW - Central Nervous System KW - Dose-Response Relationship, Drug KW - Molecular Structure KW - Piperazines KW - chemical synthesis KW - Rats KW - Receptors, Metabotropic Glutamate KW - antagonists & inhibitors KW - Structure-Activity Relationship N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.bmcl.2013.05.020 ER -