Awad, Mark M <br/><br/>
Acquired resistance to crizotinib from a mutation in CD74-ROS1.  [electronic resource] 

 -  The New England journal of medicine  Jun 2013 
 - 2395-401 p.  digital 
<br/><br/> Publication Type: Case Reports; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1533-4406 
<br/><br/><label>Standard No.: </label>10.1056/NEJMoa1215530  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adenocarcinoma--drug therapy<br/>Crizotinib<br/>Drug Resistance--genetics<br/>Fatal Outcome<br/>Female<br/>Humans<br/>Lung Neoplasms--drug therapy<br/>Middle Aged<br/>Mutation<br/>Protein Conformation<br/>Protein Kinase Inhibitors--therapeutic use<br/>Protein-Tyrosine Kinases--chemistry<br/>Proto-Oncogene Proteins--chemistry<br/>Pyrazoles--therapeutic use<br/>Pyridines--therapeutic use<br/>Structure-Activity Relationship<br/>Translocation, Genetic