TLR4 is a novel determinant of the response to paclitaxel in breast cancer. [electronic resource]
- Molecular cancer therapeutics Aug 2013
- 1676-87 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1538-8514
10.1158/1535-7163.MCT-12-1019 doi
Animals Antineoplastic Agents, Phytogenic--pharmacology Apoptosis Regulatory Proteins--genetics Autocrine Communication Breast Neoplasms--drug therapy Cell Line, Tumor Cell Survival--drug effects Disease Models, Animal Drug Resistance, Neoplasm--genetics Female Gene Expression Humans Mice Mitogen-Activated Protein Kinase 1--metabolism Mitogen-Activated Protein Kinase 3--metabolism Paclitaxel--pharmacology Phosphorylation Proto-Oncogene Proteins c-akt--metabolism Receptors, Cytokine--metabolism Toll-Like Receptor 4--genetics Transcriptional Activation--drug effects