TY - GEN AU - Aguirre,Clémentine AU - Ten Brink,Tim AU - Walker,Olivier AU - Guillière,Florence AU - Davesne,Dany AU - Krimm,Isabelle TI - BcL-xL conformational changes upon fragment binding revealed by NMR SN - 1932-6203 PY - 2014///0107 KW - Benzoates KW - chemistry KW - Binding Sites KW - Biphenyl Compounds KW - Drug Discovery KW - methods KW - Humans KW - Molecular Docking Simulation KW - Nuclear Magnetic Resonance, Biomolecular KW - Protein Binding KW - Protein Structure, Quaternary KW - Protein Structure, Secondary KW - Structural Homology, Protein KW - Surface Properties KW - Thermodynamics KW - bcl-X Protein N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1371/journal.pone.0064400 ER -