Charbord, Jérémie

High throughput screening for inhibitors of REST in neural derivatives of human embryonic stem cells reveals a chemical compound that promotes expression of neuronal genes. [electronic resource] - Stem cells (Dayton, Ohio) Sep 2013 - 1816-28 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1549-4918

10.1002/stem.1430 doi


Animals
Cell Line
Disease Models, Animal
Embryonic Stem Cells--cytology
Gene Expression Regulation--drug effects
Genes, Reporter
High-Throughput Screening Assays--methods
Humans
Huntington Disease--pathology
Luciferases--metabolism
Male
Mice
Mice, Inbred C57BL
Neural Stem Cells--cytology
Neurons--drug effects
Repressor Proteins--antagonists & inhibitors
Small Molecule Libraries--pharmacology
Transcriptome--drug effects