TY - GEN AU - Niebuhr,Birte AU - Kriebitzsch,Neele AU - Fischer,Meike AU - Behrens,Kira AU - Günther,Thomas AU - Alawi,Malik AU - Bergholz,Ulla AU - Müller,Ursula AU - Roscher,Susanne AU - Ziegler,Marion AU - Buchholz,Frank AU - Grundhoff,Adam AU - Stocking,Carol TI - Runx1 is essential at two stages of early murine B-cell development SN - 1528-0020 PY - 2013///0926 KW - Animals KW - Apoptosis KW - genetics KW - B-Lymphocytes KW - cytology KW - Binding Sites KW - Cell Differentiation KW - immunology KW - Cell Lineage KW - Cell Proliferation KW - Cell Survival KW - Chromosomes, Human, Pair 12 KW - Chromosomes, Human, Pair 21 KW - Core Binding Factor Alpha 2 Subunit KW - deficiency KW - Enhancer Elements, Genetic KW - Gene Deletion KW - Gene Expression Regulation, Developmental KW - Gene Expression Regulation, Leukemic KW - Gene Targeting KW - Genome KW - Humans KW - Ikaros Transcription Factor KW - Mice KW - Mice, Inbred C57BL KW - Precursor B-Cell Lymphoblastic Leukemia-Lymphoma KW - Protein Binding KW - Proto-Oncogene Proteins c-bcl-2 KW - metabolism KW - Trans-Activators KW - Translocation, Genetic N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1182/blood-2013-01-480244 ER -