Glycated albumin causes pancreatic β-cells dysfunction through autophagy dysfunction. [electronic resource]
- Endocrinology Aug 2013
- 2626-39 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1945-7170
10.1210/en.2013-1031 doi
Animals Apoptosis--drug effects Autophagy--drug effects Autophagy-Related Protein 5 Blotting, Western Caspase 3--metabolism Cell Line, Tumor Cell Survival--drug effects Glucose--pharmacology Glycation End Products, Advanced Green Fluorescent Proteins--genetics Heat-Shock Proteins--genetics Insulin--metabolism Insulin-Secreting Cells--drug effects Insulinoma--metabolism Islets of Langerhans--drug effects Male Microscopy, Fluorescence Microtubule-Associated Proteins--genetics Nitric Oxide Synthase Type II--genetics Proteins--genetics RNA Interference Rats Rats, Sprague-Dawley Reverse Transcriptase Polymerase Chain Reaction Sequestosome-1 Protein Serum Albumin--pharmacology Transcription Factor RelA--metabolism Glycated Serum Albumin