Disruption of thioredoxin reductase 1 protects mice from acute acetaminophen-induced hepatotoxicity through enhanced NRF2 activity. [electronic resource]
- Chemical research in toxicology Jul 2013
- 1088-96 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Intramural
1520-5010
10.1021/tx4001013 doi
Acetaminophen--toxicity Animals Chemical and Drug Induced Liver Injury--metabolism Glutathione--analysis Mice Mice, Inbred C57BL Mice, Knockout Mice, Transgenic NF-E2-Related Factor 2--genetics Thioredoxin Reductase 1--antagonists & inhibitors