Deliberate reduction of hemagglutinin and neuraminidase expression of influenza virus leads to an ultraprotective live vaccine in mice. [electronic resource]
- Proceedings of the National Academy of Sciences of the United States of America Jun 2013
- 9481-6 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
1091-6490
10.1073/pnas.1307473110 doi
Animals Blotting, Northern Blotting, Western Cross Protection Dogs Down-Regulation--genetics Hemagglutinin Glycoproteins, Influenza Virus--metabolism Influenza A Virus, H1N1 Subtype Lethal Dose 50 Madin Darby Canine Kidney Cells Male Mice Mice, Inbred BALB C Neuraminidase--metabolism Orthomyxoviridae Infections--immunology Viral Vaccines--metabolism