Yang, Chen

Deliberate reduction of hemagglutinin and neuraminidase expression of influenza virus leads to an ultraprotective live vaccine in mice. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America Jun 2013 - 9481-6 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

1091-6490

10.1073/pnas.1307473110 doi


Animals
Blotting, Northern
Blotting, Western
Cross Protection
Dogs
Down-Regulation--genetics
Hemagglutinin Glycoproteins, Influenza Virus--metabolism
Influenza A Virus, H1N1 Subtype
Lethal Dose 50
Madin Darby Canine Kidney Cells
Male
Mice
Mice, Inbred BALB C
Neuraminidase--metabolism
Orthomyxoviridae Infections--immunology
Viral Vaccines--metabolism