TY  - GEN
AU  - Wu,Yulin
AU  - Aquino,Christopher J
AU  - Cowan,David J
AU  - Anderson,Don L
AU  - Ambroso,Jeff L
AU  - Bishop,Michael J
AU  - Boros,Eric E
AU  - Chen,Lihong
AU  - Cunningham,Alan
AU  - Dobbins,Robert L
AU  - Feldman,Paul L
AU  - Harston,Lindsey T
AU  - Kaldor,Istvan W
AU  - Klein,Ryan
AU  - Liang,Xi
AU  - McIntyre,Maggie S
AU  - Merrill,Christine L
AU  - Patterson,Kristin M
AU  - Prescott,Judith S
AU  - Ray,John S
AU  - Roller,Shane G
AU  - Yao,Xiaozhou
AU  - Young,Andrew
AU  - Yuen,Josephine
AU  - Collins,Jon L
TI  - Discovery of a highly potent, nonabsorbable apical sodium-dependent bile acid transporter inhibitor (GSK2330672) for treatment of type 2 diabetes
SN  - 1520-4804
PY  - 2013///0903
KW  - Animals
KW  - Bile Acids and Salts
KW  - metabolism
KW  - Diabetes Mellitus, Type 2
KW  - drug therapy
KW  - Dogs
KW  - Drug Discovery
KW  - Drug Stability
KW  - HEK293 Cells
KW  - Humans
KW  - Hypoglycemic Agents
KW  - chemistry
KW  - Male
KW  - Methylamines
KW  - Mice
KW  - Organic Anion Transporters, Sodium-Dependent
KW  - antagonists & inhibitors
KW  - Rats
KW  - Solubility
KW  - Symporters
KW  - Thiazepines
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1021/jm400459m
ER  -