TY - GEN AU - Buqué,Aitziber AU - Aresti,Unai AU - Calvo,Begoña AU - Sh Muhialdin,Jangi AU - Muñoz,Alberto AU - Carrera,Sergio AU - Azkona,Eider AU - Rubio,Itziar AU - López-Vivanco,Guillermo TI - Thymidylate synthase expression determines pemetrexed targets and resistance development in tumour cells SN - 1932-6203 PY - 2013///1209 KW - Antimetabolites, Antineoplastic KW - pharmacology KW - Cell Line, Tumor KW - Cell Proliferation KW - drug effects KW - Cell Survival KW - Cisplatin KW - Drug Resistance, Neoplasm KW - genetics KW - Drug Synergism KW - Folic Acid Antagonists KW - Gene Expression Profiling KW - Gene Expression Regulation, Neoplastic KW - Glutamates KW - Guanine KW - analogs & derivatives KW - Humans KW - Organ Specificity KW - Pemetrexed KW - Purines KW - antagonists & inhibitors KW - Pyrimidines KW - Thymidylate Synthase N1 - Publication Type: Journal Article UR - https://doi.org/10.1371/journal.pone.0063338 ER -