Chen, Ximin

A human anti-c-Met Fab fragment conjugated with doxorubicin as targeted chemotherapy for hepatocellular carcinoma. [electronic resource] - PloS one 2013 - e63093 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1932-6203

10.1371/journal.pone.0063093 doi


Animals
Carcinoma, Hepatocellular--drug therapy
Cell Line, Tumor
Cell Survival--drug effects
Doxorubicin--chemistry
Drug Stability
Gene Expression
Hepatocytes--drug effects
Humans
Hydrogen-Ion Concentration
Immunoconjugates--chemistry
Immunoglobulin Fab Fragments--chemistry
Liver Neoplasms--drug therapy
Liver Neoplasms, Experimental--drug therapy
Male
Mice
Mice, Nude
Molecular Targeted Therapy
Peptide Library
Proto-Oncogene Proteins c-met--antagonists & inhibitors