TY - GEN AU - Bouillon,Anthony AU - Giganti,David AU - Benedet,Christophe AU - Gorgette,Olivier AU - Pêtres,Stéphane AU - Crublet,Elodie AU - Girard-Blanc,Christine AU - Witkowski,Benoit AU - Ménard,Didier AU - Nilges,Michael AU - Mercereau-Puijalon,Odile AU - Stoven,Véronique AU - Barale,Jean-Christophe TI - In Silico screening on the three-dimensional model of the Plasmodium vivax SUB1 protease leads to the validation of a novel anti-parasite compound SN - 1083-351X PY - 2013///0906 KW - Amino Acid Sequence KW - Animals KW - Antimalarials KW - chemistry KW - Binding Sites KW - genetics KW - Biocatalysis KW - drug effects KW - Dose-Response Relationship, Drug KW - Erythrocytes KW - Female KW - Kinetics KW - Malaria KW - parasitology KW - Merozoites KW - Mice KW - Models, Molecular KW - Molecular Sequence Data KW - Molecular Structure KW - Plasmodium berghei KW - Plasmodium vivax KW - Protein Structure, Tertiary KW - Protozoan Proteins KW - Sequence Homology, Amino Acid KW - Serine Proteases KW - Serine Proteinase Inhibitors KW - Sf9 Cells KW - Substrate Specificity N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1074/jbc.M113.456764 ER -