Bouillon, Anthony

In Silico screening on the three-dimensional model of the Plasmodium vivax SUB1 protease leads to the validation of a novel anti-parasite compound. [electronic resource] - The Journal of biological chemistry Jun 2013 - 18561-73 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1083-351X

10.1074/jbc.M113.456764 doi


Amino Acid Sequence
Animals
Antimalarials--chemistry
Binding Sites--genetics
Biocatalysis--drug effects
Dose-Response Relationship, Drug
Erythrocytes--drug effects
Female
Kinetics
Malaria--parasitology
Merozoites--drug effects
Mice
Models, Molecular
Molecular Sequence Data
Molecular Structure
Plasmodium berghei--drug effects
Plasmodium vivax--drug effects
Protein Structure, Tertiary
Protozoan Proteins--chemistry
Sequence Homology, Amino Acid
Serine Proteases--chemistry
Serine Proteinase Inhibitors--chemistry
Sf9 Cells
Substrate Specificity