TY - GEN AU - Mutoh,Shingo AU - Sobhany,Mack AU - Moore,Rick AU - Perera,Lalith AU - Pedersen,Lee AU - Sueyoshi,Tatsuya AU - Negishi,Masahiko TI - Phenobarbital indirectly activates the constitutive active androstane receptor (CAR) by inhibition of epidermal growth factor receptor signaling SN - 1937-9145 PY - 2013///1209 KW - Animals KW - Blotting, Western KW - Cell Line, Tumor KW - Cells, Cultured KW - Constitutive Androstane Receptor KW - Epidermal Growth Factor KW - metabolism KW - ErbB Receptors KW - chemistry KW - GABA Modulators KW - Hepatocytes KW - drug effects KW - Humans KW - Male KW - Mice KW - Mice, Inbred C3H KW - Models, Molecular KW - Phenobarbital KW - Phosphorylation KW - Protein Binding KW - Protein Phosphatase 2 KW - genetics KW - Protein Structure, Tertiary KW - RNA Interference KW - Receptors for Activated C Kinase KW - Receptors, Cell Surface KW - Receptors, Cytoplasmic and Nuclear KW - Signal Transduction N1 - Publication Type: Journal Article; Research Support, N.I.H., Intramural UR - https://doi.org/10.1126/scisignal.2003705 ER -