TY  - GEN
AU  - Mackenzie,Gerardo G
AU  - Huang,Liqun
AU  - Alston,Ninche
AU  - Ouyang,Nengtai
AU  - Vrankova,Kvetoslava
AU  - Mattheolabakis,George
AU  - Constantinides,Panayiotis P
AU  - Rigas,Basil
TI  - Targeting mitochondrial STAT3 with the novel phospho-valproic acid (MDC-1112) inhibits pancreatic cancer growth in mice
SN  - 1932-6203
PY  - 2013///1126
KW  - Animals
KW  - Antineoplastic Agents
KW  - pharmacology
KW  - Apoptosis
KW  - Cell Line, Tumor
KW  - Cimetidine
KW  - Drug Synergism
KW  - Female
KW  - Humans
KW  - Membrane Potential, Mitochondrial
KW  - drug effects
KW  - Mice
KW  - Mice, Inbred BALB C
KW  - Mice, Nude
KW  - Mitochondria
KW  - Molecular Targeted Therapy
KW  - Organophosphates
KW  - Pancreatic Neoplasms
KW  - drug therapy
KW  - Protein Transport
KW  - Reactive Oxygen Species
KW  - metabolism
KW  - STAT3 Transcription Factor
KW  - Signal Transduction
KW  - Tumor Burden
KW  - Valproic Acid
KW  - analogs & derivatives
KW  - Xenograft Model Antitumor Assays
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1371/journal.pone.0061532
ER  -