Zhao, Yujun <br/><br/>
Diastereomeric spirooxindoles as highly potent and efficacious MDM2 inhibitors.  [electronic resource] 

 -  Journal of the American Chemical Society  May 2013 
 - 7223-34 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1520-5126 
<br/><br/><label>Standard No.: </label>10.1021/ja3125417  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antineoplastic Agents--chemical synthesis<br/>Bone Neoplasms--drug therapy<br/>Bone and Bones--drug effects<br/>Cell Line, Tumor<br/>Cyclization<br/>Humans<br/>Indoles--chemical synthesis<br/>Mice, SCID<br/>Models, Molecular<br/>Osteosarcoma--drug therapy<br/>Oxindoles<br/>Proto-Oncogene Proteins c-mdm2--antagonists & inhibitors<br/>Spiro Compounds--chemical synthesis<br/>Stereoisomerism