Lacritin rescues stressed epithelia via rapid forkhead box O3 (FOXO3)-associated autophagy that restores metabolism. [electronic resource]
- The Journal of biological chemistry Jun 2013
- 18146-61 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
1083-351X
10.1074/jbc.M112.436584 doi
Amino Acid Sequence Autophagy--drug effects Autophagy-Related Protein 7 Autophagy-Related Proteins Cells, Cultured Epithelial Cells--drug effects Forkhead Box Protein O3 Forkhead Transcription Factors--genetics Glycoproteins--chemistry Homeostasis--drug effects Humans Huntingtin Protein Interferon-gamma--pharmacology Mass Spectrometry Metabolome--drug effects Molecular Sequence Data Mutation Nerve Tissue Proteins--genetics Peptides--pharmacology RNA Interference Recombinant Proteins--pharmacology Syndecan-1--genetics Tears--chemistry Tumor Necrosis Factor-alpha--pharmacology Ubiquitin-Activating Enzymes--genetics Vesicular Transport Proteins--genetics