TY  - GEN
AU  - Yang,Haijuan
AU  - Rudge,Derek G
AU  - Koos,Joseph D
AU  - Vaidialingam,Bhamini
AU  - Yang,Hyo J
AU  - Pavletich,Nikola P
TI  - mTOR kinase structure, mechanism and regulation
SN  - 1476-4687
PY  - 2013///0530
KW  - Adaptor Proteins, Signal Transducing
KW  - chemistry
KW  - Adenosine Triphosphate
KW  - Catalytic Domain
KW  - drug effects
KW  - Crystallography, X-Ray
KW  - Furans
KW  - Humans
KW  - Indoles
KW  - Magnesium
KW  - Models, Molecular
KW  - Naphthyridines
KW  - Protein Structure, Tertiary
KW  - Purines
KW  - Pyridines
KW  - Pyrimidines
KW  - Ribosomal Protein S6 Kinases, 70-kDa
KW  - metabolism
KW  - Sirolimus
KW  - Structure-Activity Relationship
KW  - TOR Serine-Threonine Kinases
KW  - antagonists & inhibitors
KW  - Tacrolimus Binding Protein 1A
KW  - mTOR Associated Protein, LST8 Homolog
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1038/nature12122
ER  -